All publications
2011
Leroy J, Richter W, Mika D, Castro LR, Abi-Gerges A, Xie M, Scheitrum C, Lefebvre F, Schittl J, Mateo P, Westenbroek R, Catterall WA, Charpentier F, Conti M, Fischmeister R, Vandecasteele G. Phosphodiesterase 4B in the cardiac L-type Ca2+ channel complex regulates Ca2+ current and protects against ventricular arrhythmias in mice. J. Clin. Invest. 2011; 121(7): 2651-61.
Bignolais O, Quang KL, Naud P, El Harchi A, Briec F, Piron J, Bourgé A, Leoni AL, Charpentier F, Demolombe S. Early ion-channel remodeling and arrhythmias precede hypertrophy in a mouse model of complete atrioventricular block. J. Mol. Cell. Cardiol. 2011 Jul 20.
Gayard M, Guilluy C, Rousselle A, Viollet B, Henrion D, Pacaud P, Loirand G, Rolli-Derkinderen M. AMPK Alpha 1-Induced RhoA Phosphorylation Mediates Vasoprotective Effect of Estradiol. Arterioscler Thromb Vasc Biol. 2011 Aug 18.
Bergaya S, Faure S, Baudrie V, Rio M, Escoubet B, Bonnin P, Henrion D, Loirand G, Achard JM, Jeunemaitre X, Hadchouel J. WNK1 regulates vasoconstriction and blood pressure response to 1-adrenergic stimulation in mice. Hypertension, 2011 58(3):439-45.
2010
Guilluy C, Brégeon J, Toumaniantz G, Rolli-Derkinderen M, Retailleau K, Loufrani L, Henrion D, Scalbert E, Bril A, Torres RM, Offermanns S, Pacaud P, Loirand G. The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure. Nat Med. 2010; 16(2): 183-90.
Leoni AL, Gavillet B, Rougier JS, Marionneau C, Probst V, Le Scouarnec S, Schott JJ, Demolombe S, Bruneval P, Huang CL, Colledge CH, Grace AA, Le Marec H, Wilde AA, Mohler PJ, Escande D, Abriel H, Charpentier F. Variable Nav1.5 protein expression from the wild-type allele correlates with phenotypic penetrance in the Scn5a+/- mouse model for cardiac conduction disease. PLoS ONE 2010; 19.5: e9298.
Renault MA, Robbesyn F, Réant P, Douin V, Daret D, Allières C, Belloc I, Couffinhal T, Arnal JF, Klingel K, Desgranges C, Dos Santos P, Charpentier F, Gadeau AP. Osteopontin expression in cardiomyocytes induces dilated cardiomyopathy. Circ Heart Fail. 2010; 3: 431-439.
Djata Cabral M, Paulet PE, Robert V, Gomes B, Renoud ML, Savignac M, Leclerc C, Moreau M, Lair D, Langelot M, Magnan A, Yssel H, Mariame B, Guery JC, Pelletier L. Knocking-down Cav1 Calcium Channels Implicated in Th2-cell Activation Prevents Experimental Asthma. Am J Respir Crit Care Med. 2010;181(12):1310-7.
Mionnet C, Buatois V, Kanda A, Milcent V, Fleury S, Lair D, Langelot M. Lacoeuille Y, Hessel E, Coffman R, Magnan A, Dombrowicz DD, Glaichenhaus N, Julia V. CX3CR1 is required for allergic airway inflammation by promoting Th2 cell survival and maintenance in inflamed lung. Nat Med. 2010;16(11):1305-12.
2009
Biliczki P, Girmatsion Z, Brandes RP, Harenkamp S, Pitard B, Charpentier F, Hébert TE, Hohnloser SH, Baró I, Nattel S, Ehrlich JR. Trafficking-deficient long QT syndrome mutation KCNQ1-T587M confers severe clinical phenotype by impairment of KCNH2 membrane localization. Heart Rhythm 2009; 6(12):1792-801.
Chaumette T, Lebouvier T, Aubert P, Lardeux B, Qin C, Li Q, Accary D, Bézard E, Bruley des Varannes S, Derkinderen P, Neunlist M. Neurochemical plasticity in the enteric nervous system of a primate animal model of experimental Parkinsonism. Neurogastroenterol Motil. 2009 21(2):215-222.
Piche T, Barbara G, Aubert P, Bruley des Varannes S, Dainese R, Nano JL, Cremon C, Stanghellini V, De Giorgio R, Galmiche JP, Neunlist M. Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of soluble mediators. Gut. 2009 58(2):196-201.
Agard C, Rolli-Derkinderen M, Dumas-de-La-Roque E, Rio M, Sagan C, Savineau JP, Loirand G, Pacaud P. Protective role of the antidiabetic drug metformin against chronic experimental pulmonary hypertension. Br. J. Pharmacol. 2009, 158(5):1285-94.
Audigane L, Kerfant BG, El Harchi A, Lorenzen-Schmidt I, Toumaniantz G, Cantereau A, Potreau D, Charpentier F, Noireaud J, Gauthier C. Rabbit, a relevant model for the study of cardiac beta 3-adrenoceptors. Exp. Physiol. 2009; 94: 400-411.
Fernandes S, van Rijen HV, Forest V, Evain S, Leblond AL, Mérot J, Charpentier F, de Bakker JM, Lemarchand P. Cardiac Cell Therapy: Overexpression of Connexin43 in Skeletal Myoblasts and Prevention of Ventricular Arrhythmias. J. Cell. Mol. Med. 2009 13(9B):3703-12
Langhi C, May CL, Gmyr V, Vandewalle B, Kerr-Conte J, Krempf M, Pattou F, Costet P, Cariou B. PCSK9 is expressed in pancreatic delta-cells and does not alter insulin secretion. Biochem Biophys Res Commun. 2009 25;390(4):1288-93
Le May C, Kourimate S, Langhi C, Chétiveaux M, Jarry A, Comera C, Collet X, Kuipers F, Krempf M, Cariou B, Costet P. Proprotein Convertase Subtilisin Kexin Type 9 null mice are protected fromm postprandial triglyceridemia. Arterioscler Thromb Vasc Biol. 2009 29(5):684-90.
Tran Quang T, Rozec B, Audigane L, Gauthier C. Investigation of the different adrenoceptor targets of nebivolol enantiomers in rat thoracic aorta. Br J Pharmacol. 2009 156(4):601-8.
Rozec B, Erfanian M, Laurent K, Trochu JN, Gauthier C. Nebivolol, a vasodilating selective beta(1)-blocker, is a beta(3)-adrenoceptor agonist in the nonfailing transplanted human heart. J Am Coll Cardiol. 2009 53(17):1532-8.
Yoshiki H, Nishimune A, Suzuki F, Morishima S, Ikeda T, Sasaki M, Audigane L, Gauthier C, Muramatsu I. Evaluation of ß1L-adrenoceptors in rabbit heart by tissue segment binding assay. Journal of Pharmacological Sciences, 2009, 110(3):389-96.
2008
Charpentier F, Bourgé A, Mérot J. Mouse models of SCN5A-related cardiac arrhythmias. Prog. Biophys. Mol. Biol. 2008 98(2-3):230-7.
Chevalier J, Derkinderen P, Gomes P, Thinard R, Naveilhan P, Vanden Berghe P, Neunlist M. Activity-dependent regulation of tyrosine hydroxylase expression in the enteric nervous system. J Physiol. 2008 Apr 1;586(7):1963-75.
Gellen B, Fernández-Velasco M, Briec F, Vinet L, LeQuang K, Rouet-Benzineb P, Bénitah JP, Pezet M, Palais G, Pellegrin N, Zhang A, Perrier R, Escoubet B, Marniquet X, Richard S, Jaisser F, Gómez AM, Charpentier F, Mercadier JJ. Conditional FKBP12.6 overexpression in mouse cardiac myocytes prevents triggered ventricular tachycardia through specific alterations in excitation-contraction coupling. Circulation 2008;117(14):1778-86.
Guilluy C, Rolli-Derkinderen M, Loufrani L, Bourgé A, Henrion D, Sabourin L, Loirand G, Pacaud P. Ste20-Related Kinase SLK Phosphorylates Ser188 of RhoA to Induce Vasodilation in Response to Angiotensin II Type 2 Receptor Activation. Circ Res. 2008;102(10):1265-74.
Kourimate S., Le May C., Langhi C., Jarnoux AL., Ouguerram K., Zaïr Y., Nguyen P., Krempf M., Cariou B., and Costet P.. Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9. J. Biol. Chem. 2008 Apr 11;283(15):9666-73.
Langhi C., Le May C., Kourimate S., Caron S., Staels B., Krempf M., Costet P., Cariou B.. Activation of the farnesoid X receptor represses pcsk9 expression in human hepatocytes. FEBS Lett. 2008 Mar 19;582(6):949-955.
Lebouvier T, Chaumette T, Damier P, Coron E, Touchefeu Y, Vrignaud S, Naveilhan P, Galmiche JP, Bruley des Varannes S, Derkinderen P, Neunlist M. Pathological lesions in colonic biopsies during Parkinson’s disease. Gut. 2008 Dec;57(12):1741-3.
Loirand G, Rolli-Derkinderen M, Pacaud P. Urotensin II and atherosclerosis. Peptides.2008 May;29(5):778-82.
Loirand G, Scalbert E, Bril A, Pacaud P. Rho exchange factors in the cardiovascular system. Curr Opin Pharmacol. 2008, 8(2):174-180.
Neunlist M, Van Landeghem L, Bourreille A, Savidge T. Neuro-glial crosstalk in inflammatory bowel disease. J Intern Med. 2008 Jun;263(6):577-83.
Piron J, Quang KL, Briec F, Amirault JC, Leoni AL, Desigaux L, Escande D, Pitard B, Charpentier F. Biological Pacemaker Engineered by Nonviral Gene Transfer in a Mouse Model of Complete Atrioventricular Block. Mol. Ther. 2008;16(12):1937-43.
