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Frey S, Ayer A, Sotin T, Lorant V, Louis-Gaubert C, Arnaud L, Billon-Crossouard S, Croyal M, Prieur X, Hadjadj S, Cariou B, Blanchard C, Le May C. Single-anastomosis duodeno-ileal bypass with sleeve gastrectomy improves lipid and glucose homeostasis in ob/ob mice. Obesity 2024 Jan;32(1):91-106.






 Peterlin P, Garnier A, Le Bourgeois A, Guillaume T, Le Bris Y, Theisen O, Béné MC, Eveillard M, Rimbert M, Jullien M, Planche L, Gaschet J, Chevallier P. Tocilizumab in combination with a standard induction chemotherapy in acute myeloid leukaemia patients (TOCILAM study): a single-centre, single-arm, phase 1 trial.  EClinicalMedicine. 2023 Sep 28;64:102254.


Klein M, Dijoux E, Cheminant MA, Intes L, Bouchaud G. GliSODin® prevents airway inflammation by inhibiting T-cell differentiation and activation in a mouse model of asthma. Front Allergy. 2023 Jun 6;4:1199355. 


Blandin A, Amosse J, Froger J, Hilairet G, Durcin M, Fizanne L, Ghesquière V, Prieur X, Chaigneau J, Vergori L, Dray C, Pradère JP, Blandin S, Dupont J, Ducluzeau PH, Dubois S, Boursier J, Cariou B, Le Lay S. Extracellular vesicles are carriers of adiponectin with insulin-sensitizing and anti-inflammatory properties. Cell Rep. 2023 Aug 29;42(8):112866.


Terrill JR, Huchet C, Le Guiner C, Lafoux A, Caudal D, Tulangekar A, Bryson-Richardson RJ, Sztal TE, Grounds MD, Arthur PG. Muscle Pathology in Dystrophic Rats and Zebrafish Is Unresponsive to Taurine Treatment, Compared to the mdx Mouse Model for Duchenne Muscular Dystrophy. Metabolites. 2023 Feb 4;13(2):232.


Jaque-Fernandez F, Allard B, Monteiro L, Lafoux A, Huchet C, Jaimovich E, Berthier C, Jacquemond V. Probenecid affects muscle Ca2+ homeostasis and contraction independently from pannexin channel block. J Gen Physiol. 2023 Apr 3;155(4):e202213203.

Dijoux E, Klein M, Misme-Aucouturier B, Cheminant MA, de Carvalho M, Collin L, Hassoun D, Delage E, Gourdel M, Loirand G, Sauzeau V, Magnan A, Bouchaud G. Allergic Sensitization Driving Immune Phenotyping and Disease Severity in a Mouse Model of Asthma. Allergy Asthma Immunol Res. 2023 Mar;15(2):246-261.





André-Grégoire G, Maghe C, Douanne T, Rosińska S, Spinelli F, Thys A, Trillet K, Jacobs KA, Ballu C, Dupont A, Lyne AM, Cavalli FMG, Busnelli I, Hyenne V, Goetz JG, Bidère N, Gavard J. Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma. iScience. 2022 Sep 13;25(10):105118


Delwarde C, Toquet C, Aumond P, Kayvanjoo AH, Foucal A, Le Vely B, Baudic M, Lauzier B, Blandin S, Véziers J, Paul-Gilloteaux P, Lecointe S, Baron E, Massaiu I, Poggio P, Rémy S, Anegon I, Le Marec H, Monassier L, Schott JJ, Mass E, Barc J, Le Tourneau T, Merot J, Capoulade R. Multimodality imaging and transciptomics to phenotype mitral valve dystrophy in a unique knock-in Filamin-A rat model. Cardiovasc Res. 2022 Aug 24:cvac136


Dupas T, Pelé T, Dhot J, Burban M, Persello A, Aillerie V, Erraud A, Tesse A, Stevant D, Blangy-Letheule A, Menguy C, Sauzeau V, De Waard M, Rozec B, Gauthier C, Lauzier B. The Endothelial Dysfunction Could Be a Cause of Heart Failure with Preserved Ejection Fraction Development in a Rat Model. Oxid Med Cell Longev. 2022 May 18;2022:7377877


Giang N, Mars M, Moreau M, Mejia JE, Bouchaud G, Magnan A, Michelet M, Ronsin B, Murphy GG, Striessnig J, Guéry JC, Pelletier L, Savignac  Separation of the CaV 1.2-CaV 1.3 calcium channel duo prevents type 2 allergic airway inflammation.  M. Allergy. 2022 Feb;77(2):525-539.


Montnach J, Blömer LA, Lopez L, Filipis L, Meudal H, Lafoux A, Nicolas S, Chu D, Caumes C, Béroud R, Jopling C, Bosmans F, Huchet C, Landon C, Canepari M, De Waard M. In vivo spatiotemporal control of voltage-gated ion channels by using photoactivatable peptidic toxins. Nat Commun. 2022 Jan 20;13(1):417.


Bourdon A, François V, Zhang L, Lafoux A, Fraysse B, Toumaniantz G, Larcher T, Girard T, Ledevin M, Lebreton C, Hivonnait A, Creismeas A, Allais M, Marie B, Guguin J, Blouin V, Remy S, Anegon I, Huchet C, Malerba A, Kao B, Le Heron A, Moullier P, Dickson G, Popplewell L, Adjali O, Montanaro F, Le Guiner C. Evaluation of the dystrophin carboxy-terminal domain for micro-dystrophin gene therapy in cardiac and skeletal muscles in the DMDmdx rat model. Gene Ther. 2022 Feb 1.


Jaque-Fernandez F, Allard B, Monteiro L, Lafoux A, Huchet C, Jaimovich E, Berthier C, Jacquemond V. Probenecid affects sarcoplasmic reticulum Ca2+ release and depresses contractile activation in mouse skeletal muscle J Gen Physiol. 2022 Sep 5;154(9):e2021ecc23.




Creisméas A, Gazaille C, Bourdon A, Lallemand MA, François V, Allais M, Ledevin M, Larcher T, Toumaniantz G, Lafoux A, Huchet C, Anegon I, Adjali O, Le Guiner C, Fraysse B. J TRPC3, but not TRPC1, as a good therapeutic target for standalone or complementary treatment of DMD. Transl Med. 2021 Dec 20;19(1):519. 


Klein M, Misme-Aucouturier B, Cheminant MA, De Carvalho M, Wauters M, Tranquet O, Magnan A, Bouchaud G. Engineering a safe monoclonal anti-human IL-2 that is effective in a murine model of food allergy and asthma Allergy 2021 Jul 29.


Blangy-Letheule A, Persello A, Michelland S, Cunin V, Souab F, Aillerie V, Dhot J, Erraud A, Montnach J, Seve M, Bourgoin-Voillard S, Rozec B, De Waard M, Lauzier B. The Secretome Deregulations in a Rat Model of Endotoxemic Shock Oxid Med Cell Longev 2021 Jul 24;2021:6650464.


Pochard C, Gonzales J, Bessard A, Mahe MM, Bourreille A, Cenac N, Jarry A, Coron E, Podevin J, Meurette G, Neunlist M, Rolli-Derkinderen M. PGI2 Inhibits Intestinal Epithelial Permeability and Apoptosis to Alleviate Colitis. Cell Mol Gastroenterol Hepatol. 2021 May 7:S2352-345X(21)00090-4


Dilasser F, Rose L, Hassoun D, Klein M, Rousselle M, Brosseau C, Guignabert C, Taillé C, Dombret MC, Di Candia L, Heddebaut N, Bouchaud G, Pretolani M, Magnan A, Loirand G, Sauzeau V. Essential role of smooth muscle Rac1 in severe asthma-associated airway remodelling. Thorax. 2021 Feb 4.


Dhot J, Prat V, Ferron M, Aillerie V, Erraud A, Rozec B, Waard M, Gauthier C, Lauzier B. Implications of a Soy-Based Diet for Animal Models. Int J Mol Sci. 2021 Jan 14;22(2):774.




Klein M, Colas L, Cheminant MA, Brosseau C, Sauzeau V, Magnan A, Bouchaud G. Der p 2.1 Peptide Abrogates House Dust Mites-Induced Asthma Features in Mice and Humanized Mice by Inhibiting DC-Mediated T Cell Polarization. Front Immunol. 2020 11:565431


Margier M, Le May C, Antoine T, Halimi C, Nowicki M, Lespine A, Reboul E. P-glycoprotein (ABCB1) is involved in vitamin K efflux Food Chem 2020 Nov 1;128510


Dupas T, Denis M, Dontaine J, Persello A, Bultot L, Erraud A, Vertommen D, Bouchard B, Tessier A, Rivière M, Lebreton J, Bigot-Corbel E, Montnach J, De Waard M, Gauthier C, Burelle Y, Olson AK, Rozec B, Des Rosiers C, Bertrand L, Issad T, Lauzier B. Protein O-GlcNAcylation levels are regulated independently of dietary intake in a tissue and time-specific manner during rat postnatal development. Acta Physiol (Oxf). 2020 Oct 6:e13566.


Lafoux A, Lotteau S, Huchet C, Ducreux S. The contractile phenotype of skeletal muscle in TRPV1 knockout mice is gender specific and exercise-dependent. Life 2020 Oct 10,233


Caudal D, François V, Lafoux A, Ledevin M, Anegon I, Le Guiner C, Larcher T, Huchet C. Characterization of brain dystrophins absence and impact in dystrophin-deficient Dmdmdx rat model. PLoS One. 2020 Mar 11;15(3)


Seiller C, Maiga S, Touzeau C, Bellanger C, Kervoëlen C, Descamps G, Maillet L, Moreau P, Pellat-Deceunynck C, Gomez-Bougie P, Amiot M. Dual targeting of BCL2 and MCL1 rescues myeloma cells resistant to BCL2 and MCL1 inhibitors associated with the formation of BAX/BAK hetero-complexes. Cell Death Dis. 2020 May 5;11(5):316


Moui A, Klein M, Hassoun D, Dijoux E, Cheminant MA, Magnan A, Bouchaud G. The IL-15/sIL-15Rα complex modulates immunity without effect on asthma features in mouse. Respir Res. 2020 Jan 29;21(1):33





Ferron M, Cadiet J, Persello A, Prat V, Denis M, Erraud A, Aillerie V, Mevel M, Bigot E, Chatham JC, Gauthier C, Rozec B, Lauzier B. O-GlcNAc stimulation: A new metabolic approach to treat septic shock. Sci Rep. 2019 Dec 10;9(1):18751


Ouisse LH, Remy S, Lafoux A, Larcher T, Tesson L, Chenouard V, Guillonneau C, Brusselle L, Vimond N, Rouger K, Péréon Y, Chenouard A, Gras-Le Guen C, Braudeau C, Josien R, Huchet C, Anegon I. Immunophenotype of a Rat Model of Duchenne’s Disease and Demonstration of Improved Muscle Strength After Anti-CD45RC Antibody Treatment. Front Immunol. 2019 Sep 9;10:2131


Aubert P, Guinobert I, Blondeau C, Bardot V, Ripoche I, Chalard P, Neunlist M. Basal and Spasmolytic Effects of a Hydroethanolic Leaf Extract of Melissa officinalis L. on Intestinal Motility: An Ex Vivo Study. J Med Food. 2019 Jul;22(7):653-662.


Coué M, Tesse A, Falewée J, Aguesse A, Croyal M, Fizanne L, Chaigneau J, Boursier J, Ouguerram K. Spirulina Liquid Extract Protects against Fibrosis Related to Non-Alcoholic Steatohepatitis and Increases Ursodeoxycholic Acid. Nutrients. 2019 Jan 18;11(1)





Regnault C, Usal M, Veyrenc S, Couturier K, Batandier C, Bulteau AL, Lejon D, Sapin A, Combourieu B, Chetiveaux M, Le May C, Lafond T, Raveton M, Reynaud S. Unexpected metabolic disorders induced by endocrine disruptors in Xenopus tropicalis provide new lead for understanding amphibian decline. Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4416-E4425


André-Grégoire G, Dilasser F, Chesné J, Braza F, Magnan A, Loirand G, Sauzeau V. Targeting of Rac1 prevents bronchoconstriction and airway hyperresponsiveness. J Allergy Clin Immunol. 2018 Sep;142(3):824-833.


Castan L, Cheminant MA, Colas L, Brouard S, Magnan A, Bouchaud G. Food allergen-sensitized CCR9+ lymphocytes enhance airways allergic inflammation in mice. Allergy. 2018 Jul;73(7):1505-1514.


Dumontet C, Beck G, Gardebien F, Haudecoeur R, Mathé D, Matera EL, Tourette A, Mattei E, Esmenjaud J, Boyère C, Nurisso A, Peuchmaur M, Pérès B, Bouchaud G, Magnan A, Monneret G, Boumendjel A. Piperidinyl-embeded chalcones possessing anti PI3Kδ inhibitory properties exhibit anti-atopic properties in preclinical models. Eur J Med Chem. 2018 Oct 5;158:405-413.





Caudal D, Guinobert I, Lafoux A, Bardot V, Cotte C, Ripoche I, Chalard P, Huchet C.  Skeletal muscle relaxant effect of a standardized extract of Valeriana officinalis L. after acute administration in mice. J Tradit Complement Med. 2017 Oct 12;8(2):335-340.


Carbone ML, Chadeuf G, Heurtebise-Chrétien S, Prieur X, Quillard T, Goueffic Y, Vaillant N, Rio M, Castan L, Durand M, Baron-Menguy C, Aureille J, Desfrançois J, Tesse A, Torres RM, Loirand G. Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis. J Clin Invest. 2017 127(12):4516-4526.


Derangeon M, Montnach J, Cerpa CO, Jagu B, Patin J, Toumaniantz G, Girardeau A, Huang CLH, Colledge WH, Grace AA, Baró I, Charpentier F. Transforming growth factor β receptor inhibition prevents ventricular fibrosis in a mouse model of progressive cardiac conduction disease. Cardiovasc Res. 2017 – 113(5):464-474. 


Harford-Wright E, Andre-Gregoire G, Jacobs KA, Treps L, Le Gonidec S, Leclair HM, Gonzalez-Diest S, Roux Q, Guillonneau F, Loussouarn D, Oliver L, Vallette FM, Foufelle F, Valet P, Davenport AP, Glen RC, Bidere N, Gavard J. Pharmacological targeting of apelin impairs glioblastoma growth. Brain. 2017 Nov 1;140(11):2939-2954.







Lafoux A, Baudry C, Bonhomme C, Le Ruyet P, Huchet C. Soluble Milk Protein Supplementation with Moderate Physical Activity Improves Locomotion Function in Aging Rats. PLoS One. 2016 Dec 14;11(12):e0167707


Portero V, Le Scouarnec S, Es-Salah-Lamoureux Z, Burel S, Gourraud JB, Bonnaud S, Lindenbaum P, Simonet F, Violleau J, Baron E, Moreau E, Scott C, Chatel S, Loussouarn G, O’Hara T, Mabo P, Dina C, Le Marec H, Schott JJ, Probst V, Baró I, Marionneau C, Charpentier F, Redon R. Dysfunction of the Voltage-Gated K+ Channel β2 Subunit in a Familial Case of Brugada Syndrome. J Am Heart Assoc. 2016 Jun 10;5(6) .


Brégeon J., Coron E., Da Silva AC., Jaulin J., Aubert P., Chevalier J., Vergnolle N., Meurette G., Neunlist M. Sacral nerve stimulation enhances early intestinal mucosal repair following mucosal injury in a pig model. J Physiol. 2016 594(15):4309-23.


Randriamboavonjy J, Loirand G, Vaillant N, Lauzier B, Derbré S, Michalet S, Pacaud P, Tesse A. Cardiac Protective Effects of Moringa oleifera Seeds in Spontaneous Hypertensive Rats. Am J Hypertens. 2016 Jul;29(7):873-81.





Rocheteau P, Chatre L, Briand D, Mekarki M, Jouvion G, Bardon J, Crochemore C, Serrani P, Lecci PP, Latil M, Matot B, Carlier PG, Latronico N, Huchet C, Lafoux A, Sharshar T, Ricchetti M, Chretien F. Sepsis induces long-term metabolic and mitochondrial muscle stem cell dysfunction amenable by mesenchymal stem cell therapy. Nat. Commun. 2015 Dec 15;6:10145.


Pochard C, Coquenlorge S, Jaulin J, Cenac N, Vergnolle N, Meurette G, Freyssinet M, Neunlist M, Rolli-Derkinderen M. Defects in 15-HETE production and control of epithelial permeability by human enteric glial cells from patients with Crohn’s disease. Gastroenterology 2015 Sep 30. pii: S0016-5085(15)01394-3. 


Jouni M, Si-Tayeb K, Es-Salah-Lamoureux Z, Latypova X, Champon B, Caillaud A, Rungoat A, Charpentier F, Loussouarn G, Baro I, Zibara K, Lemarchand P, Gaborit N. Toward personalized medicine: Using cardiomyocytes differentiated from urine-derived pluripotent stem cells to recapitulate electrophysiological characteristics of type 2 long QT syndrome. J Am Heart Assoc. 2015;4:e002159. 


Bouchaud G, Gourbeyre P, Bihouée T, Aubert P , Lair D, Cheminant MA, Denery-Papini S, Neunlist M, Magnan A and Bodinier M. Consecutive food and respiratory allergies amplify systemic and gut but not lung outcomes in mice.  Agric. Food Chem. 2015, 63, 6475−83.


Berger JM, Vauillant N, Le May C, Calderon C, Brégeon J, Prieur X, Hadchouel J, Loirand G, Cariou B. PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension. Atherosclerosis. 2015 Mar;239(1):252-9. 


Chesné J, Braza F, Chadeuf G, Mahay G, Cheminant MA, Loy J, Brouard S, Sauzeau V, Loirand G, Magnan A. Prime role of IL-17A in neutrophilia and airway smooth muscle contraction in a house dust mite-induced allergic asthma model. J Allergy Clin Immunol. 2015 ;135(6):1643-1643.e3.





Larcher T, Lafoux A, Tesson L, Remy S, Thepenier V, François V, Le Guiner C, Goubin H, Dutilleul M, Guigand L, Toumaniantz G, De Cian A, Boix C, Renaud JB, Cherel Y, Giovannangeli C, Concordet JP, Anegon I, Huchet C. Characterization of dystrophin deficient rats: a new model for duchenne muscular dystrophy. PLoS One. 2014 13;9(10):e110371


Targeting PI3Kγ activity decreases vascular trauma-induced intimal hyperplasia through modulation of the Th1 response. Smirnova NF, Gayral S, Pedros C, Loirand G, Vaillant N, Malet N, Kassem S, Calise D, Goudounèche D, Wymann MP, Hirsch E, Gadeau AP, Martinez LO, Saoudi A, Laffargue M. J Exp Med. 2014;211(9):1779-92

Food allergy enhances allergic asthma in mice. Bihouée T, Bouchard G, Chesné J, Lair D, Rolland-Debord C, Braza F, Cheminant MA, Aubert P, Mahay G, Sagan C, Neunlist M, Brouard S, Bodinier M, Magnan A. Respir Res. 2014 Nov 30;15(1):142




Effects of oral administration of rotenone on gastrointestinal functions in mice. Tasselli M, Chaumette T, Paillusson S, Monnet Y, Lafoux A, Huchet-Cadiou C, Aubert P, Hunot S, Derkinderen P, Neunlist M. Neurogastroenterol Motil. 2013; 25(3):e183-93.


Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the Liver X Receptor. Ducheix S, Montagner A, Polizzi A, Lasserre F, Marmugi A, Bertrand-Michel J, Podechard N, Saati TA, Chétiveaux M, Baron S, Boué J, Dietrich G, Mselli-Lakhal L, Costet P, Lobaccaro JM, Pineau T, Theodorou V, Postic C, Martin PG, Guillou H. J Hepatol. 2013; 58(5):984-92.


Rakotomalala G, Agard C, Tonnerre P, Tesse A, Derbré S, Michalet S, Hamzaoui J, Rio M, Cario-Toumaniantz C, Richomme P, Charreau B, Loirand G, Pacaud P. Extract from Mimosa pigra attenuates chronic experimental pulmonary hypertension. J Ethnopharmacol. 2013; 148(1):106-16.


Chantôme A, Potier-Cartereau M, Clarysse L, Fromont G, Marionneau-Lambot S, Guéguinou M, Pagès JC, Collin C, Oullier T, Girault A, Arbion F, Haelters JP, Jaffrès PA, Pinault M, Besson P, Joulin V, Bougnoux P, Vandier C. Pivotal role of the lipid Raft SK3-Orai1 complex in human cancer cell migration and bone metastases. Cancer Res. 2013; 73(15):4852-61.


Potiron V, Abderrahmani R, Clément-Colmou K, Marionneau-Lambot S, Oullier T, Paris F, Supiot S. Improved functionality of the vasculature during conventionally fractionated radiation therapy of prostate cancer. PLoS One 2013; 8(12):e84076.





Vinet L, Pezet M, Bito V, Briec F, Biesmans L, Rouet-Benzineb P, Gellen B, Prévilon M, Chimenti S, Vilaine JP, Charpentier F, Sipido KR, Mercadier JJ. Cardiac FKBP12.6 overexpression protects against triggered ventricular tachycardia in pressure overloaded mouse hearts. Basic Res. Cardiol. 2012; 107(2): 1-14.





Pre-clinical study of 21 approved drugs in the mdx mouse. Carre-Pierrat M, Lafoux A, Tanniou G, Chambonnier L, Divet A, Fougerousse F, Huchet-Cadiou C, Ségalat L. Neuromuscul Disord. 2011;21(5):313-27.



Bignolais O, Quang KL, Naud P, El Harchi A, Briec F, Piron J, Bourgé A, Leoni AL, Charpentier F, Demolombe S. Early ion-channel remodeling and arrhythmias precede hypertrophy in a mouse model of complete atrioventricular block. J. Mol. Cell. Cardiol. 2011; 51(5): 713-21.


Gayard M, Guilluy C, Rousselle A, Viollet B, Henrion D, Pacaud P, Loirand G, Rolli-Derkinderen M. AMPK Alpha 1-Induced RhoA Phosphorylation Mediates Vasoprotective Effect of Estradiol. Arterioscler Thromb Vasc Biol. 2011; 31(11): 2634-42.


Bergaya S, Faure S, Baudrie V, Rio M, Escoubet B, Bonnin P, Henrion D, Loirand G, Achard JM, Jeunemaitre X, Hadchouel J. WNK1 regulates vasoconstriction and blood pressure response to 1-adrenergic stimulation in mice. Hypertension, 2011 58(3):439-45.





Guilluy C, Brégeon J, Toumaniantz G, Rolli-Derkinderen M, Retailleau K, Loufrani L, Henrion D, Scalbert E,  Bril A, Torres RM, Offermanns S, Pacaud P, Loirand G. The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure. Nat Med. 2010; 16(2): 183-90.


Leoni AL, Gavillet B, Rougier JS, Marionneau C, Probst V, Le Scouarnec S, Schott JJ, Demolombe S, Bruneval P, Huang CL, Colledge CH, Grace AA, Le Marec H, Wilde AA, Mohler PJ, Escande D, Abriel H, Charpentier F. Variable Nav1.5 protein expression from the wild-type allele correlates with phenotypic penetrance in the Scn5a+/- mouse model for cardiac conduction disease. PLoS ONE 2010; 19.5: e9298.


Renault MA, Robbesyn F, Réant P, Douin V, Daret D, Allières C, Belloc I, Couffinhal T, Arnal JF, Klingel K, Desgranges C, Dos Santos P, Charpentier F, Gadeau AP. Osteopontin expression in cardiomyocytes induces dilated cardiomyopathy. Circ Heart Fail. 2010; 3: 431-39.


Djata Cabral M, Paulet PE, Robert V, Gomes B, Renoud ML, Savignac M, Leclerc C, Moreau M, Lair D, Langelot M, Magnan A, Yssel H, Mariame B, Guery JC, Pelletier L. Knocking-down Cav1 Calcium Channels Implicated in Th2-cell Activation Prevents Experimental Asthma. Am J Respir Crit Care Med. 2010;181(12):1310-7.


Mionnet C, Buatois V, Kanda A, Milcent V, Fleury S, Lair D, Langelot M. Lacoeuille Y, Hessel E, Coffman R, Magnan A, Dombrowicz DD, Glaichenhaus N, Julia V. CX3CR1 is required for allergic airway inflammation by promoting Th2 cell survival and maintenance in inflamed lung. Nat Med. 2010;16(11):1305-12.





Biliczki P, Girmatsion Z, Brandes RP, Harenkamp S, Pitard B, Charpentier F, Hébert TE, Hohnloser SH, Baró I, Nattel S, Ehrlich JR. Trafficking-deficient long QT syndrome mutation KCNQ1-T587M confers severe clinical phenotype by impairment of KCNH2 membrane localization. Heart Rhythm 2009; 6(12):1792-801.


Chaumette T, Lebouvier T, Aubert P, Lardeux B, Qin C, Li Q, Accary D, Bézard E, Bruley des Varannes S, Derkinderen P, Neunlist M. Neurochemical plasticity in the enteric nervous system of a primate animal model of experimental Parkinsonism. Neurogastroenterol Motil. 2009 21(2):215-22.


Piche T, Barbara G, Aubert P, Bruley des Varannes S, Dainese R, Nano JL, Cremon C, Stanghellini V, De Giorgio R, Galmiche JP, Neunlist M. Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of soluble mediators. Gut. 2009 58(2):196-201.


Agard C, Rolli-Derkinderen M, Dumas-de-La-Roque E, Rio M, Sagan C, Savineau JP, Loirand G, Pacaud P. Protective role of the antidiabetic drug metformin against chronic experimental pulmonary hypertension. Br. J. Pharmacol. 2009, 158(5):1285-94.


Audigane L, Kerfant BG, El Harchi A, Lorenzen-Schmidt I, Toumaniantz G, Cantereau A, Potreau D, Charpentier F, Noireaud J, Gauthier C. Rabbit, a relevant model for the study of cardiac beta 3-adrenoceptors. Exp. Physiol. 2009; 94: 400-11.


Fernandes S, van Rijen HV, Forest V, Evain S, Leblond AL, Mérot J, Charpentier F, de Bakker JM, Lemarchand P. Cardiac Cell Therapy: Overexpression of Connexin43 in Skeletal Myoblasts and Prevention of Ventricular Arrhythmias. J. Cell. Mol. Med. 2009 13(9B):3703-12


Langhi C, May CL, Gmyr V, Vandewalle B, Kerr-Conte J, Krempf M, Pattou F, Costet P, Cariou B. PCSK9 is expressed in pancreatic delta-cells and does not alter insulin secretion. Biochem Biophys Res Commun. 2009 25;390(4):1288-93


Le May C, Kourimate S, Langhi C, Chétiveaux M, Jarry A, Comera C, Collet X, Kuipers F, Krempf M, Cariou B, Costet P. Proprotein Convertase Subtilisin Kexin  Type 9 null mice are protected fromm postprandial triglyceridemia. Arterioscler Thromb Vasc Biol. 2009 29(5):684-90.


Tran Quang T, Rozec B, Audigane L, Gauthier C. Investigation of the different adrenoceptor targets of nebivolol enantiomers in rat thoracic aorta. Br J Pharmacol. 2009 156(4):601-8.

Rozec B, Erfanian M, Laurent K, Trochu JN, Gauthier C. Nebivolol, a vasodilating selective beta(1)-blocker, is a beta(3)-adrenoceptor agonist in the nonfailing transplanted human heart. J Am Coll Cardiol. 2009 53(17):1532-38.


Yoshiki H, Nishimune A, Suzuki F, Morishima S, Ikeda T, Sasaki M, Audigane L, Gauthier C, Muramatsu I. Evaluation of ß1L-adrenoceptors in rabbit heart by tissue segment binding assay. Journal of Pharmacological Sciences, 2009, 110(3):389-96.





Charpentier F, Bourgé A, Mérot J. Mouse models of SCN5A-related cardiac arrhythmias. Prog. Biophys. Mol. Biol. 2008 98(2-3):230-7.


Chevalier J, Derkinderen P, Gomes P, Thinard R, Naveilhan P, Vanden Berghe P, Neunlist M. Activity-dependent regulation of tyrosine hydroxylase expression in the enteric nervous system. J Physiol. 2008 Apr 1;586(7):1963-75.


Gellen B, Fernández-Velasco M, Briec F, Vinet L, LeQuang K, Rouet-Benzineb P, Bénitah JP, Pezet M, Palais G, Pellegrin N, Zhang A, Perrier R, Escoubet B, Marniquet X, Richard S, Jaisser F, Gómez AM, Charpentier F, Mercadier JJ. Conditional FKBP12.6 overexpression in mouse cardiac myocytes prevents triggered ventricular tachycardia through specific alterations in excitation-contraction coupling. Circulation 2008;117(14):1778-86.


Guilluy C, Rolli-Derkinderen M, Loufrani L, Bourgé A, Henrion D, Sabourin L, Loirand G, Pacaud P. Ste20-Related Kinase SLK Phosphorylates Ser188 of RhoA to Induce Vasodilation in Response to Angiotensin II Type 2 Receptor Activation. Circ Res. 2008;102(10):1265-74.


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Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the Liver X Receptor.

Effects of oral administration of rotenone on gastrointestinal functions in mice.